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New disease mechanism discovered for Syt1-associated disorder

Neurotransmitter release is less synchronized in Syt1-associated disorder, according to a new study from the Cornelisse lab (FGA) led by Maaike van Boven and published in Molecular Psychiatry

PoC grant awarded to Karen Laupman and Nathaniel Bell

PhD candidates Karen Laupman and Nathaniel Bell, with supervisors Associate Professor Vivi Heine and Professor Danielle Posthuma, have been awarded a Proof of Concept (PoC) grant for €55.000 from Amsterdam Neuroscience for their innovative research on repurposing drugs specifically for schizophrenia (SCZ).

Reward sensitivity plays a role in youth crime

Boys who associate with delinquent friends are more likely to display antisocial behavior. A new study by neuroscientists and behavior experts from Vrije Universiteit Amsterdam and Amsterdam UMC, led by CNCR colleague Jorim Tielbeek (dept. of Complex Trait Genetics) shows that this association is stronger in boys with an increased sensitivity to reward.

SynGO consortium releases version 1.2 with 30% more genes

The SynGO consortium, consisting of >20 expert labs worldwide and coordinated by CNCR, brings together scientific knowledge about synapses & provides online analysis tools. Their new release contains >1600 annotated synaptic genes.

ESCO consortium takes off with new funding and EMA application

The European STXBP1 COnsortium (ESCO, www.stxbp1eu.org) was established in 2021 with eight partner countries in the EU, coordinated by VU/AUMC. All partners have now signed the consortium agreement and ESCO secured its 1st funding.

What makes us human? Detailed cellular maps of the entire human

An international team of neuroscientists under leadership of Ed Lein and Hongkui Zeng worked on studies to map the cell types that make up the human brain. VU scientists Natalia Goriounova, Christiaan de Kock and Huib Mansvelder and their teams also contributed to this together with neurosurgeons from the VUmc.

New study on Axon Initial Segment plasticity in Science Advances

A new study led by Amelie Freal (FGA) describes mechanisms controlling Axon Initial Segment plasticity, revealing distinct and dynamic pools of sodium channels that adjust neuronal excitability

Precision medicine boosted by TKI grant to N=You center

With 750 kEUR funding from TKI, Hilgo Bruining and Klaus Linkenkaer-Hansen have teamed up with the company Clouds of Care in a public-private partnership to accelerate research and implementation of EEG analysis for precision medicine in patients with epilepsy or children with a neurodevelopmental disorder like autism.

ERC Starting Grant for Amélie Freal

Amélie Freal (FGA) was awarded an ERC Starting Grant by the European Union for the “PLaisTICITY” project to investigate mechanisms underlying Axon Initial Segment plasticity

ZonMW Dementia Fellowship for Kim de Kleijn

Kim de Kleijn (The Candidate Center/AUMC/FGA) received the ZonMW Dementia Fellowship (3 years) to set-up an independent research line to study the TREM receptor family and its relevance for microglia functioning in context of Alzheimer’s disease.

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Amsterdam Neuroscience

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Fax + 31 20 598 92 81
email: brigitte.borgman@vu.nl

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